Bioinformatics Map of the Beta-Globin Gene

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Questions to Consider

  1. What is represented by the red letters? Black letters? Blue letters?bioinformatics-beta-globin-map.jpg                                                                                                                 (Click to make image larger)
  2. Which strand of DNA is considered the template strand?  How do you know? bioinformatics-beta-globin-data.jpg
  3. Why are there three rows (reading frames) of amino acid data?
  4. Consider the region that is highlighted below.  Is this an intron or exon? beta-globin-exon.jpg
  5. How many exons and introns does the beta-globin gene contain?
  6. When you completed this activity, you noticed that the exons were located in different reading frames.  What caused this?
  7. What is the alternative splicing hypothesis?

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